Uji Aktivitas UV Protektif Secara In Vivo pada Krim dari Bahan Aktif Cangkang Telur Ayam Ras Menggunakan Hewan Coba Kelinci Betina

Previously, an in vitro study of the SPF value a cream formulation with active ingredients from broiler eggshells was conducted using UV-vis spectrophotometry at wavelength 290-320 nm and obtained 8.335 concentration 9000 ppm. This aims to continue testing UV protective activity vivo on creams these combination adding 5% titanium dioxide. The experimental animals used consisted 12 female rabbits divided into 4 groups, namely (1) positive control: market product spf 15, (2) Negative base, (3) Formula I: (15% egg shell), (4 ) II: (a 15% eggshell dioxide). test carried out by determining (SPF) against UV-B rays groups comparing Minimum Erythema Dose (MED) protected skin those not sunscreen. results were then analyzed based category sunscreen uv protection. showed Group 1; 2; 3 respectively 15.3; 0 ; 8.55 12.37. has same as group 1 better than 3.